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Updated: Aug 14, 2026

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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Refractory Coronary No-Reflow Reversed by Prolonged Intracoronary Nitroprusside Via an Innovative Microcatheter
Yanfu Wang1, Xiaolu Li1, Wei Li1
1Department of Cardiovascular Medicine, Aviation General Hospital, Beijing, China.
JACC. Case Reports
|August 13, 2026
Summary
Refractory coronary no-reflow (CNR) can be treated with prolonged, localized sodium nitroprusside infusion. This innovative method successfully restored blood flow and preserved ventricular function in patients with delayed myocardial infarction presentation.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Refractory coronary no-reflow (CNR) lacks effective localized management strategies when standard treatments fail.
- Delayed presentation of ST-segment elevation myocardial infarction poses treatment challenges.

