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Updated: Aug 15, 2026

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates
06:48

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates

Published on: January 5, 2024

Multi-step binding-unbinding pathways govern properties of biomolecular condensates

Bhanjan Debnath1, Parag Katira2

  • 1Department of Mechanical Engineering, San Diego State University, CA 92182, USA; Department of Chemical Engineering, IIT Hyderabad, Kandi, Sangareddy, Telangana 502285, India.

Biophysical Journal
|August 14, 2026
PubMed
Summary

Biomolecular interactions shape cellular condensates. Different binding mechanisms yield distinct interaction lifetime distributions, impacting condensate dynamics like material exchange and aging, even with constant average lifetimes.

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