Related Experiment Video
Updated: Aug 15, 2026

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
Published on: August 1, 2025
Adolescent-Centered Cannabis Messaging in Clinical Settings: Preliminary Qualitative Insights From Adolescents for
Pravesh Sharma1, Hannah Kolarik2, Payton Jorgenson2
1Department of Psychiatry and Psychology, Mayo Clinic Health System, Eau Claire, WI, USA.
Background:
Youth-directed cannabis messaging is often generic, adult-centered, and does not reflect contemporary patterns of cannabis use. This study examined adolescents' perceptions of cannabis-related messaging and identified messaging strategies they find relevant.
Methods:
The authors conducted qualitative interviews with adolescents aged 14-17 years with past 30-day cannabis use. Interviews were analyzed using thematic analysis with constant comparison. Data collection continued until no new themes were identified (N = 7).
Results:
Adolescents reported that fear-based and abstinence-only messaging were ineffective. They viewed nonjudgmental, autonomy-supportive, and youth-centered messaging as more credible. Participants emphasized that clinicians should acknowledge the perceived benefits of cannabis to build trust and credibility. Messages that focused on immediate consequences of cannabis use, such as brain fog and memory impairment, were more effective than generalized long-term harms. Adolescents expressed greater trust in harm reduction messaging and communication strategies that integrate real-world adolescent experiences with clinician expertise.
Conclusions:
These preliminary findings suggest that clinicians should consider framing cessation messaging around cognition and memory. Although the long-term goal is cannabis cessation, clinicians should remain ready to transition toward harm reduction guidance, based on adolescents' receptiveness and their response to initial abstinence-focused conversation, reflecting an adaptive framework that shifts in intensity and orientation with the patient's response rather than following a static treatment algorithm. Although these strategies may enhance engagement and mitigate treatment dropout, larger-scale studies are needed before these strategies can be broadly recommended for clinical practice. Ethical incorporation of peer-lived experiences to support harm reduction and cessation should be considered.
Related Concept Videos
Cognitive Development During Adolescence
Influence of Parents and Peers on Identity
Parental Influence on Identity Development
Parents serve as primary guides and managers in an adolescent's life, offering support instrumental in decision-making and personal growth. This guiding role...
Ethnic Identity within a Larger Culture
Drug Abuse and Addiction: Pharmacological Phenomena
Modeling in Therapy
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
An Overview of Psychoactive Drugs
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
