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Double-Layered Antibiotic-Loaded Cement Spacer for Hip Infection: A Report of Two Cases
Akira Yuasa1, Hiroki Kobayashi2
1Department of Orthopedic Surgery, Japan Self-Defense Forces Central Hospital, Tokyo, Japan.
Journal of Orthopaedic Case Reports
|August 14, 2026
Summary
A novel double-layered antibiotic cement spacer effectively treats hip infections and implant complications. This method offers sustained antibiotic release and mechanical stability during two-stage reconstruction, leading to successful patient recovery.
Area of Science:
- Orthopedic surgery
- Infectious disease
- Biomaterials science
Background:
- Septic arthritis of the hip and periprosthetic joint infection (PJI) are severe conditions leading to joint damage and functional loss.
- Two-stage reconstruction with antibiotic-loaded cement spacers is common for advanced hip joint destruction or infection.
- Conventional polymethylmethacrylate (PMMA) spacers have limited antibiotic release duration and risk of inactivation.