Related Experiment Video
Updated: Aug 15, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Catheter-Associated Urinary Tract Infections (CAUTI) and Central Line-Associated Bloodstream Infections (CLABSI) in
Amber Prasad1, Minakshi Singh2, Puneet K Gupta3
1Microbiology, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.
Background:
Catheter-associated urinary tract infections (CAUTI) and central line-associated bloodstream infections (CLABSI) are important preventable device-associated healthcare-related infections in critical care settings and are associated with prolonged hospitalization, adverse outcomes, and increased treatment burden. This study evaluated the incidence and trends of these infections in the critical care units of a tertiary care hospital during the study period.
Methodology:
This was a retrospective analysis of routinely collected surveillance records from the critical care units of a tertiary care teaching hospital from July 2019 to December 2020. Standard surveillance definitions were applied throughout. Data on patient-days, device-days, CAUTI events, CLABSI events, device utilization, and hand hygiene compliance were collected and analyzed. Trends across the pre-pandemic and pandemic periods were compared, and the association between hand hygiene compliance and infection rates was assessed.
Results:
During the study period, 30,263 patient-days, 16,943 urinary catheter-days, and 11,891 central line-days were recorded. A total of 43 CAUTI events and 138 CLABSI events were identified. Infection rates varied across months and units, with higher burdens observed in some adult critical care areas and among lower birth-weight groups in the neonatal intensive care unit. CLABSI rates increased substantially during the pandemic period compared with the pre-pandemic period, while CAUTI rates also showed variation over time. Hand hygiene compliance remained low during the surveillance period.
Conclusions:
Device-associated infection rates remained high in the critical care units studied and worsened during the pandemic period, particularly for CLABSI. Strengthening device-care practices, maintaining surveillance systems, and improving hand hygiene compliance remain essential to reducing infection burden in tertiary critical care settings.
Related Concept Videos
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Urine Studies II: Urine Culture and Sensitivity Test
Urinary Tract Infection I: Introduction
Urinary Tract Infection II: Pathophysiology

