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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Evaluation of Weak Interactions Between the Ring Component and Axle Component in [2]Rotaxanes With 1,3-Diyne Moiety
Taichi Ohseki1, Akira Nagayama1, Jun Miyazaki2
1Department of Chemistry, Faculty of Science, Tokyo University of Science, Shinjuku, Tokyo, Japan.
Abstract:
Weak interactions between the macrocyclic phenanthroline derivatives and hydrocarbon moieties were quantitatively evaluated by analyzing the NMR spectra of the rotaxanes. The observed associative interaction between the macrocycle and the 1,3-diyne moiety was further investigated by DFT calculations. The C─H⋯N interaction and reduced steric bulk of the 1,3-diyne moiety were assumed to be the origins of the interaction. These findings demonstrate that rotaxane architectures provide a powerful platform for the quantitative analysis of weak interactions.
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