Related Experiment Video
Updated: Aug 15, 2026

A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis
Published on: June 4, 2016
Resolving the Phylogenetic Placement of the FSfaCV/PCV5-Related Viruses Within the Genus Macochavirus
Wenqiang Wang1, Liping Jiang1, Tingting Niu2
1Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China, yzu.edu.cn.
Abstract:
Metagenomic analysis of fecal samples from diarrheic pigs in China identified 10 complete circular single-stranded DNA viral genomes previously designated as putative porcine circovirus 5 (PCV5)-like viruses. Genome characterization revealed a typical cressdnavirus organization with bidirectionally oriented Rep and Cap genes. Phylogenetic analyses based on complete genomes and encoded proteins showed that these viruses do not cluster with members of Circoviridae but instead form a distinct lineage within the family Pecoviridae, closely related to the genus Macochavirus. Sequence identity, genetic distance, and nucleotide diversity analyses supported their classification as a coherent viral group. Comparative analyses indicated greater sequence divergence in the Rep region than in the Cap region. These findings support reclassification of putative PCV5 as a porcine-associated lineage within the genus Macochavirus, designated porcine Macochavirus (PMV), thereby resolving their long-standing taxonomic ambiguity and expanding the recognized diversity of cressdnaviruses within the family Pecoviridae.
More Related Videos
09:50Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation
Published on: October 27, 2019
08:56Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
Published on: July 27, 2018
Related Concept Videos
Phylogenetic Species Concept in Microbiology
Microbial Phylogeny
Inhibitors of Virion Maturation and Assembly
Phylogeny
Modern Molecular Taxonomy
Retrovirus Life Cycles