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Updated: Aug 16, 2026
Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
Published on: May 5, 2018
Fetal Vascular Malperfusion: A Comprehensive 10-Year Retrospective Single-Center Cohort Analysis
Background:
Fetal vascular malperfusion (FVM) represents a significant cause of adverse perinatal outcomes, yet population-specific patterns remain understudied in Middle Eastern populations. This study characterizes FVM patterns and clinical correlates in Kuwait over a 10-year period.
Methods:
Retrospective analysis of 180 histologically confirmed FVM cases from the Maternity Hospital, Kuwait (2014-2024). Cases were classified by FVM grade, associated pathology, and clinical parameters.
Results:
High-grade FVM predominated (80.0%, 144/180). Distinct trimester-specific patterns emerged: second trimester showed highest inflammatory pathology (18.6%), while maternal vascular malperfusion (MVM) occurred exclusively in third trimester pregnancies (10.7%). Maternal age analysis revealed unexpected peak risk in 30-34 years group (88.3% high-grade FVM). Twin pregnancies demonstrated significantly higher pathological burden (88.9% vs 79.5% in singletons, p = 0.041).
Conclusions:
This study reveals distinct FVM patterns in Middle Eastern populations, including unique age-related risks and trimester-specific pathological profiles. These findings support population-specific approaches to FVM assessment and management.
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