CLINICAL CHARACTERISTICS OF INFECTION-ASSOCIATED PALMOPLANTAR DERMATOSIS IN PREPUBERTAL CHILDREN: AN OBSERVATIONAL STUDY
Related Experiment Video
Updated: Aug 16, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
1European University, Department of Dermatology, Tbilisi; 2Kanveni - National Center of Dermatology and Venereology, Georgia.
Insights
Pediatric palmoplantar dermatoses, often infectious, typically present as symmetrical, uniform rashes in children. Treatment focuses on the underlying cause, though COVID-19-associated cases require symptomatic care and further study.
Area of Science:
- Pediatric Dermatology
- Dermatopathology
- Infectious Diseases
Background:
- Pediatric dermatoses can differ from adult presentations, with palmoplantar (foot and hand) skin conditions posing unique diagnostic challenges.
- Acral rashes in children may be localized or part of a generalized skin condition, stemming from diverse etiological factors.
Purpose of the Study:
- To characterize the clinical features of pediatric palmoplantar dermatoses.
- To correlate these features with patient age and specific underlying diseases.
- To establish evidence-based treatment recommendations for various palmoplantar dermatoses in children.
Main Methods:
- An observational study involving 58 children aged 1-10 years (2020-2024).
- Diagnostic methods included comprehensive dermatological history, dermatoscopy, microscopy, and bacteriological examinations.
- Clinical evaluation focused on rash distribution, uniformity, and symmetry.
Main Results:
- The most common diagnoses were scabies (37.9%), impetigo (19%), and hand-foot-and-mouth disease (13.8%).
- Infections like scabies and impetigo often presented as symmetrical and uniform rashes (67.2% uniform, 58.6% symmetrical).
- COVID-19-associated dermatoses showed distinct clinical patterns requiring further investigation.
Conclusions:
- Infection-related palmoplantar dermatoses in prepubertal children typically manifest with symmetrical and uniform rashes.
- Treatment strategies should target the primary underlying infection.
- COVID-19-associated palmoplantar dermatoses exhibit unique characteristics necessitating symptomatic treatment and continued research due to their nonspecific presentation.
Introduction:
Dermatoses that develop in children often differ from similar pathologies in adults. One of the interesting and ongoing subjects of study for pediatric dermatology is pathologies of the skin of the palmoplantar areas. Rashes in the acral area may be part of a widespread rash, or a pathology specifically expressed only in the acral area. Similar problems in pediatric dermatological practice are determined by a wide range of etiological factors.
Aim:
The aim of the study was to identify the characteristic clinical features of palmoplantar dermatoses in children in relation to age and different diseases; to determine basic recommendations for a specific pathology.
Material And Methods:
The observational study includes data processing of 58 patients aged 1-10 years from 2020-2024. The diagnostic components included a complete dermatological history and dermatoscopic, microscopic, and cultural (bacteriological) examinations.
Results:
The mean age of the patients was 5.5 years. 27 (46.6%) were female, 31 (53.4%) were male. Patients with palmoplantar dermatoses were clinically evaluated based on the distribution, uniformity and symmetry of the rash. In 24(41,4%) cases, the rash was a local lesion, in 34(58,6%) it was part of a generalized rash. 34(58, 6%) of children had a symmetrical rash, 24(41,4%) had an asymmetric rash; 39(67,2%) of patients had uniform rash, and 19(32,8%)% had several types. Based on clinical diagnosis, the following groups were distinguished: scabies 22 (37.9%), impetigo 11 (19%), scabies and impetigo 4 (6.9%), tinea 6 (10.3%), hand-foot-and-mouth disease 8 (13.8%), and Covid-19-associated 7 (12.1%) palmoplantar dermatoses.
Conclusion:
In prepubertal children, the majority of palmoplantar dermatoses associated with infections characterized by a predominantly symmetrical and uniform rash. Treatment recommendations focus on the treatment of the underlying disease. COVID-19-associated palmoplantar dermatoses have a different course, treatment is limited to symptomatic therapy, and the nonspecificity of the manifestations requires further scientific research.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Staphylococcal Skin Infections