Related Experiment Video
Updated: Aug 16, 2026
03:23
Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
Published on: March 17, 2023
Decision for Preservation or Ligation of Aberrant Left Hepatic Artery Using Fluorescence Imaging in Minimally
Ji Eun Jung1, Shiyeol Jun1, Seyeol Oh2
1Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Summary
Near-infrared fluorescence imaging safely guides aberrant left hepatic artery management during gastrectomy, reducing liver complication risks. This technique evaluates liver perfusion to inform preservation or ligation decisions.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
- Medical Imaging
Background:
- Radical gastrectomy requires careful management of the aberrant left hepatic artery (ALHA) to balance oncologic outcomes and liver complications.
- Developing a decision-making algorithm for ALHA preservation or ligation is crucial.
Purpose of the Study:
- To develop and evaluate an algorithm for ALHA management during gastrectomy.
- To utilize near-infrared fluorescence imaging for assessing liver perfusion in real-time.
Main Methods:
- A prospective, multicenter study involving 50 patients undergoing minimally invasive gastrectomy.
- Indocyanine green (ICG) fluorescence imaging assessed left hepatic lobe perfusion after temporary ALHA clamping.
- Patients were grouped by perfusion defect (No Perfusion, Partial Perfusion, Complete Perfusion) to guide ALHA management.
Main Results:
- No adverse events related to ICG injection were reported.
- The Partial Perfusion group showed significant increases in AST and ALT levels postoperatively.
- All liver enzyme levels normalized within five days, with no severe liver-related complications observed within one month.
Conclusions:
- Real-time near-infrared fluorescence imaging effectively guides ALHA management during gastrectomy.
- This imaging technique helps minimize the risk of postoperative liver dysfunction.
- Further research is needed to confirm the safety of ALHA ligation across all observed perfusion patterns.
