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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Aspergillus-derived indole diketopiperazines (IDKPs): chemical diversity, biosynthetic logics, and therapeutic

Jing Tian1, Huanhuan Yang1, Huawei Zhang1

  • 1School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China; Zhejiang-Egypt Joint Laboratory on Intelligent Discovery of Marine Drugs, Zhejiang University of Technology, Hangzhou 310014, China; State Key Laboratory of Green Chemical Synthesis and Conversion, Zhejiang University of Technology, Hangzhou 310014, China.

Fitoterapia
|August 14, 2026
PubMed

Keywords:
AspergillusBiosynthesisChemical diversityIndole diketopiperazineStructure-activity relationship (SAR)

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