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Acbd7 is essential for preserving hair cell-mediated auditory and vestibular function

Mingxuan Wu1,2,3,4, Gaogan Jia1,2,3,4, Yanyan Jia1,2,3,4,5

  • 1ENT Institute and Department of Otorhinolaryngology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.

Experimental & Molecular Medicine
|August 14, 2026
PubMed
Summary

Acyl-CoA binding domain-containing 7 (Acbd7) is vital for maintaining auditory and vestibular hair cell function. Acbd7 deficiency leads to hair cell degeneration and synaptic defects, highlighting its role in calcium signaling and fatty acid metabolism for inner ear health.

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