Association Between Subjective Symptom Severity and Radiologic Involvement in CRSwNP Patients Using SNOT-22 and...

Area of Science:

• Otolaryngology
• Medical Imaging
• Clinical Research

Background:

• Chronic rhinosinusitis with nasal polyps (CRSwNP) significantly impacts quality of life.
• Established methods for assessing CRSwNP include subjective symptom scores and objective radiologic evaluations.
• The correlation between subjective and objective measures in CRSwNP requires further elucidation.

Purpose of the Study:

• To investigate the association between symptom severity and radiologic disease extent in patients with CRSwNP.
• To explore the influence of comorbidities like asthma and Samter's triad on disease burden in CRSwNP.

Main Methods:

• A cross-sectional study involving 141 CRSwNP patients.
• Symptom burden assessed using the Persian version of the Sinonasal Outcome Test-22 (SNOT-22).
• Radiologic disease extent evaluated with the Lund-Mackay computed tomography (CT) scoring system; Spearman's correlation used for analysis.

Main Results:

• A moderate positive correlation (r = 0.347, p < 0.001) was observed between SNOT-22 and Lund-Mackay CT scores.
• Patients with asthma or Samter's triad exhibited significantly higher SNOT-22 and Lund-Mackay scores (p < 0.001).

Conclusions:

• A moderate association exists between subjective symptom severity and objective radiologic findings in CRSwNP.
• Comorbidities such as asthma and Samter's triad are associated with increased disease burden.
• Integrating subjective and objective assessments is recommended for comprehensive CRSwNP evaluation and personalized treatment strategies.