Related Experiment Video
Updated: Aug 17, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Does pre-operative left ventricular function predict mitral valve function after anomalous left coronary artery from
Raji Venkitachalam1, Katherine Cashen2, Christopher W Mastropietro3
1Division of Pediatric Cardiology and Pediatric Critical Care, Department of Pediatrics, Children's Wisconsin, Medical College of Wisconsin, Milwaukee, Wis.
Objective:
To compare the progression of mitral valve (MV) function before and after anomalous left coronary artery from the pulmonary artery (ALCAPA) repair in those with preserved versus impaired left ventricular (LV) function.
Methods:
This is a post-hoc analysis of patients who underwent repair for ALCAPA at 22 Collaborative Research from the Pediatric Cardiac Intensive Care Society centers. Mitral regurgitation (MR) severity was compared on the basis of LV function at diagnosis and through 3 years of follow-up.
Results:
Among 228 patients, 76 had normal/mild LV dysfunction and 152 had moderate/severe LV dysfunction (median ejection fraction 60% vs 23%, P < .0001). Preoperatively, moderate or greater MR was more common with moderate/severe LV dysfunction (51% vs 26%, P < .001). At 3-year follow-up, those with moderate or greater MR decreased significantly in this group (51% to 13%; odds ratio, 0.11; 95% CI, 0.05-0.25; P < .0001), with no significant change in the normal/mild LV dysfunction group (26% to 16%; OR, 0.28; 95% CI, 0.06-1.39; P = .12).
Conclusions:
In patients with ALCAPA and MV dysfunction with preserved LV function, MV recovery is less common, highlighting the consideration for concomitant MV repair.
More Related Videos
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
Published on: April 24, 2017
07:28Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Related Concept Videos
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Mitral Regurgitation I: Introduction