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Isolated Adenoidectomy for Pediatric Sleep-Disordered Breathing: A Systematic Review and Meta-analysis
Hussein Smaily1,2,3, Sara Benchekroun4, Evana Francis1,2
1Department of Otolaryngology-Head & Neck Surgery, Université Laval, Quebec, Quebec, Canada.
Insights
Isolated adenoidectomy effectively treats pediatric sleep-disordered breathing (SDB) and upper airway obstruction (UAO), improving symptoms in 75% of children. It may be a conservative option for select patients, but further trials are needed.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Respiratory Medicine
Background:
- Pediatric sleep-disordered breathing (SDB) and upper airway obstruction (UAO) significantly impact child health.
- Adenotonsillectomy is a common treatment, but isolated adenoidectomy is considered for specific cases.
Purpose of the Study:
- To evaluate the efficacy of isolated adenoidectomy for pediatric SDB and UAO.
- To assess symptomatic improvement and the need for subsequent surgeries.
Main Methods:
- Systematic review and meta-proportion analysis of 22 observational studies (4460 children).
- Searched MEDLINE, EMBASE, and CENTRAL databases.
- Followed PRISMA guidelines for data extraction and bias assessment.
Main Results:
- Isolated adenoidectomy reduced the apnea-hypopnea index by 11.3 events/h.
- Pooled symptomatic improvement was 75% (95% CI 60-88).
- 17% (95% CI 11-24) required further surgical intervention; outcomes were better in children >3 years.
Conclusions:
- Isolated adenoidectomy improves objective and subjective outcomes in pediatric SDB/UAO.
- It can be a conservative alternative to adenotonsillectomy in carefully selected children.
- High-quality randomized controlled trials are needed for confirmation.
Objective:
To evaluate the efficacy of isolated adenoidectomy in managing pediatric sleep-disordered breathing (SDB) and upper airway obstruction (UAO).
Data Sources:
MEDLINE, EMBASE, and CENTRAL were systematically searched from inception through March 2025.
Review Methods:
Following Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, we included studies reporting outcomes of isolated adenoidectomy in children with SDB and UAO. Two reviewers independently screened studies, extracted data, and assessed risk of bias. A meta-proportion analysis was conducted to evaluate symptomatic improvement and the need for further surgical intervention.
Results:
Twenty-two observational studies including 4460 children were analyzed. The weighted mean age was 5.2 years. Isolated adenoidectomy led to a mean apnea-hypopnea index reduction of 11.3 events/h across four studies. The pooled proportion of symptomatic improvement was 75% (95% CI 60-88), while the pooled rate of further surgical intervention was 17% (95% CI 11-24). Subgroup analyses suggested greater symptomatic improvement and lower reoperation rates in children older than 3 years.
Conclusion:
Isolated adenoidectomy improves both objective sleep parameters and subjective outcomes. In appropriately selected children, it may represent a conservative alternative to adenotonsillectomy. These findings, however, require confirmation through well-designed randomized controlled trials.
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