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Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
Published on: August 7, 2018
Redox-State-Driven Site Selectivity and Kinetic Gating in Polyoxovanadate Methylation
1Department of Chemistry, University of Iowa, Iowa City, Iowa52240, United States.
None:
Polyoxovanadate clusters offer atomically defined platforms for studying how electronic structure influences reactivity at molecular metal-oxide surfaces. In this computational study, we investigated the coupling between reduction state and alkylation reactivity in the hexavanadate cluster [V6O13(TRIOLX)2]2- (TRIOL = tris(hydroxymethyl)methane; X = -CH3, -NO2) through a systematic analysis of successive methylation and reduction pathways using density functional theory and microkinetic modeling. The calculations show that changes in electron count redistribute the nucleophilicity of bridging μ2-oxo ligands, leading to redox-dependent regioselectivity during sequential methylation. Microkinetic simulations further indicate that several thermodynamically accessible intermediates do not accumulate because they are rapidly consumed in subsequent transformations, consistent with the need for stepwise synthetic strategies to isolate certain dimethylated species. In addition, substituent effects on the TRIOL ligands follow Hammett-type correlations, allowing rapid estimation of electronic trends without additional quantum chemical calculations. Overall, the results provide a detailed picture of how reduction state influences accessibility and selectivity during polyoxovanadate methylation.
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