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Published on: January 26, 2019
Pediatricians' attitudes and knowledge of RSV immunization products: A multi-country cross-sectional survey
Costanza Di Chiara1,2,3, Pierre-Philippe Piché-Renaud2,4, Vera Rigamonti3,5
1Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.
Insights
Pediatricians show support for respiratory syncytial virus (RSV) immunization but have limited knowledge of new strategies like nirsevimab and maternal vaccines. Addressing these knowledge gaps and logistical barriers is key for successful RSV prevention.
Area of Science:
- Pediatrics
- Immunology
- Public Health
Background:
- Respiratory syncytial virus (RSV) poses a significant health risk to infants.
- Nirsevimab and maternal vaccination are novel strategies for RSV prevention.
- Understanding healthcare provider perspectives is crucial for implementing new immunization programs.
Purpose of the Study:
- To assess pediatricians' knowledge, attitudes, and perceived barriers regarding RSV immunization strategies in Italy, Cyprus/Greece, and Spain.
- To compare these perspectives between countries with and without nirsevimab implementation.
- To inform the optimal rollout of new RSV prevention methods.
Main Methods:
- A survey was administered to 578 pediatricians across Spain, Italy, and Cyprus/Greece in July-August 2024.
- Data collected included occupational characteristics and knowledge, attitudes, and practices towards palivizumab, nirsevimab, and maternal RSV vaccines.
- Descriptive and univariate statistical analyses were performed, with a focus on Spain and Italy due to response distribution.
Main Results:
- Pediatricians generally recognized RSV risk factors but demonstrated average-to-low knowledge of nirsevimab (55.9%) and maternal vaccines (86.0%).
- Despite knowledge gaps, a high percentage of pediatricians expressed willingness (85.9%) and support (92.2%) for nirsevimab administration.
- Key barriers identified included unfamiliarity with nirsevimab and logistical challenges, with 47.4% favoring the maternal vaccine over nirsevimab.
Conclusions:
- Pediatricians are supportive of RSV immunization initiatives.
- Gaps in knowledge regarding nirsevimab and maternal vaccines, alongside logistical hurdles, may impede the early implementation of these strategies.
- Enhanced educational efforts are essential to boost the uptake of RSV immunizations and improve prevention outcomes.
Objective:
Nirsevimab and the maternal vaccination in pregnancy are newly introduced prevention strategies against respiratory syncytial virus (RSV). This study evaluated pediatricians' knowledge, attitudes, and barriers to RSV immunization in Italy and Cyprus/Greece, where nirsevimab had not yet been implemented, and in Spain, where it was introduced in 2023/2024.
Methods:
A survey was distributed to pediatricians across Spain, Italy, and Cyprus/Greece in July-August/2024. Occupational characteristics, and knowledge, attitudes and practices toward palivizumab, nirsevimab, and the maternal vaccine were collected. Of 578 respondents (response rate = 19.3%), 50% were from Spain, 40% from Italy, and 10% from Cyprus/Greece. As 90% of responses came from Spain and Italy, the main analysis focused on these two countries. Descriptive and univariate analyses (Chi-square or Fisher's exact tests) were conducted.
Results:
Respondents included pediatricians from community (51.7%), tertiary (30.4%), and primary/secondary care (17.9%) settings. Pediatricians were generally aware of RSV risk factors, without differences across countries. However, 245 (55.9%) and 375 (86.0%) participants reported average-to-low knowledge of nirsevimab and the maternal vaccine, respectively, with differences across countries (p = 0.002). Despite limited knowledge, 311 (85.9%) pediatricians were willing to administer nirsevimab, and 319 (92.2%) supported its use for all infants. Nirsevimab administration's barriers, including unfamiliarity and logistical challenges, were cited by 69 (20.0%) pediatricians. Regarding immunization preferences, 165 (47.4%) pediatricians were very likely to support the maternal vaccine over nirsevimab.
Conclusions:
While pediatricians support RSV immunization, knowledge gaps and logistical barriers may hinder early-stage implementation. Optimizing education on RSV immunization will be crucial to improve uptake and prevention strategies.
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