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Does age matter? Comparing post-operative outcomes following gastrostomy tube placement in young children: A
Alexa G Turpin1, Brenna Rachwal1, Lindsey Asti1
1Nemours Surgical Outcomes Center and Department of Surgery, Nemours Children's Health, Delaware Valley, Wilmington, DE, USA.
Insights
Young infants under 60 days old face higher complication risks after gastrostomy tube (GT) placement. Delaying GT procedures in this fragile group may improve outcomes and reduce post-operative morbidity.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Outcomes Research
Background:
- Gastrostomy tube (GT) placement is common in infants requiring nutritional support.
- Younger infants may experience increased risks and complications post-procedure.
- A prolonged nasogastric tube (NGT) feeding trial is sometimes considered for very young infants.
Purpose of the Study:
- To investigate the association between age at gastrostomy tube (GT) placement and the incidence of post-operative complications.
- To identify age-related risks for complications following GT insertion in pediatric patients.
Main Methods:
- Analysis of the American College of Surgeons' National Surgical Quality Improvement Program-Pediatric database (2014-2024).
- Inclusion of pediatric patients (0-18 months) undergoing GT placement, excluding those with major concurrent procedures.
- Multivariable logistic regression to identify factors associated with 30-day complications, comparing age groups: <60 days, 60 days to 6 months, and 7-18 months.
Main Results:
- A total of 33,973 patients were analyzed; 25.0% were <60 days old.
- Infants <60 days had the highest 30-day complication rate (12.4%) compared to older groups (9.3% and 6.6%; p<0.0001).
- Younger age (<60 days), prematurity, comorbidities, ASA class, and steroid use were associated with increased morbidity; length of stay was significantly longer in infants <6 months.
Conclusions:
- Infants younger than 60 days exhibit a significantly higher proportion of 30-day complications after gastrostomy tube placement.
- The findings suggest that delaying GT placement in very young, fragile infants may reduce post-operative complications and improve outcomes.
Purpose:
Young infants may be at higher risk of complications after gastrostomy tube (GT) placement and may benefit from a prolonged nasogastric tube (NGT) feeding trial. The purpose of this study was to determine whether age at time of GT placement is associated with post-operative complications.
Methods:
Using the American College of Surgeons' National Surgical Quality Improvement Program-Pediatric database, we identified children aged 0-18 months who underwent GT placement between 2014 and 2024. Patients who underwent major concurrent procedures were excluded. A multivariable logistic regression model was used to identify factors associated with 30-day complications. We compared composite 30-day complications across three age groups: 1) <60 days, 2) 60 days to 6 months, and 3) 7- to 18 months.
Results:
We identified 33,973 patients, 25.0% were <60 days, 45.7% were 60 days to 6 months, and 29.3% were 7- to 18 months. Patients <60 days had the highest percentage of 30-day complications (12.4%), compared to patients 60 days to 6 months (9.3%) and 7- to 18 months (6.6%) (p < 0.0001). On multivariable regression, age was associated with post-operative morbidity, as were prematurity, underlying comorbidities, ASA class, and steroid use. Post-operative length of stay (LOS) was longest in patients <60 days [6 days, interquartile range (IQR) 4-10] and patients 60 days to 6 months (6 days, IQR 2-10) compared to patients 7- to 18 months (2 days, IQR 1-4) (p < 0.0001).
Conclusions:
Children aged <60 days have the highest proportion of 30-day complications following GT placement. Because of the known fragility of very young infants, delaying GT placement in this age group may confer some benefit.
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