Much Ado About a Mutation: Congenital Melanocytic Nevus With LINC00518 and Preferentially Expressed Antigen in

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Updated: Aug 19, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Racquel A Bitar1,2, Tatiana F Abrantes3, Holly Neale4

  • 1Department of Internal Medicine, UMass Chan Medical School, Worcester, Massachusetts, USA.

Pediatric Dermatology
|August 18, 2026
PubMed

Insights

A non-invasive molecular test for congenital melanocytic nevi (CMN) showed concerning markers in a pediatric patient. This highlights potential pitfalls of applying unvalidated tests in children, even for stable nevi.

Area of Science:

  • Dermatology
  • Pediatric Oncology
  • Molecular Diagnostics

Background:

  • Small and medium congenital melanocytic nevi (CMN) generally pose a low risk for malignant transformation.
  • Non-invasive molecular tests are emerging for nevus assessment, but their pediatric validation is limited.
Keywords:
childgene expressiongenetic markersmelanomanevus

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