Related Experiment Video
Updated: Aug 19, 2026
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
Articular Manifestations in Inflammatory Bowel Disease: A Retrospective Study From a Moroccan Tertiary Care Center
Fatimaezzahra Lairani1, Jihane Rizkou1, Fatimaezzahra Chakor1
1Gastroenterology and Hepatology, Mohammed VI University Hospital Center, Marrakech, MAR.
Background:
Articular manifestations are among the most common extraintestinal manifestations of inflammatory bowel disease (IBD) and may precede, accompany, or follow intestinal symptoms. Their recognition is clinically important because delayed diagnosis can lead to functional impairment and structural damage.
Methods:
We conducted a retrospective descriptive study in the Department of Hepato-Gastroenterology at Mohammed VI University Hospital, Marrakech, Morocco. Patients with confirmed IBD and associated rheumatologic manifestations who were followed between December 2023 and December 2024 were included. Epidemiological, clinical, biological, radiological, therapeutic, and outcome data were extracted from medical records and analyzed using Microsoft Excel 2019 (Microsoft Corporation, Redmond, USA).
Results:
Among 150 patients with IBD, 60 had articular manifestations, corresponding to a prevalence of 40%. Crohn disease (CD) was present in 33 patients (55%), ulcerative colitis (UC) in 24 patients (40%), and indeterminate colitis in three patients (5%). There was a female predominance, with 41 women (68.3%) and 19 men (31.7%). Articular symptoms occurred after the diagnosis of intestinal disease in 37 patients (61.7%), before it in 17 patients (28.3%), and concomitantly in six patients (10%). Mixed axial and peripheral involvement was the most frequent pattern, observed in 35 patients (58.3%), followed by isolated peripheral involvement in 16 patients (26.7%) and isolated axial involvement in nine patients (15%). Inflammatory back pain was reported in 44 patients (73.3%), buttock pain in 37 patients (61.7%), and radiographic sacroiliitis in 25 patients (41.7%). Human leukocyte antigen B27 (HLA-B27) was positive in three of 33 tested patients (9.1%).
Conclusions:
Articular manifestations were frequent in this Moroccan IBD cohort and were dominated by mixed axial and peripheral involvement. Systematic screening for musculoskeletal symptoms in patients with IBD and close collaboration between gastroenterologists and rheumatologists are essential for early diagnosis, optimized management, and prevention of functional impairment.
Related Concept Videos
01:20Inflammatory Bowel Disease IV: Clinical Manifestations
01:25Inflammatory Bowel Disease III: Crohn's Disease
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
01:26Inflammatory Bowel Disease I: Introduction
01:17Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...