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Evolving Heart Failure Profiles in Quebec from 1998-2021: Insights from the Vision C+ Database
Shweta Todkar1,2, Emmanuel Marier-Tétrault3, Pierre Yves Turgeon2,4
1Faculté de pharmacie, Université Laval, Quebec City, Quebec, Canada.
Insights
This study analyzed heart failure (HF) patient data from Quebec
Area of Science:
- Cardiology
- Public Health
- Health Informatics
Background:
- Heart failure (HF) impacts over 750,000 Canadians, leading to significant hospitalizations.
- Specialized HF clinics offer structured care, but population-level data are scarce.
- The Vision C+ dataset, established in 1998, offers a comprehensive view of HF patient characteristics in Quebec.
Purpose of the Study:
- To describe changes in heart failure patient characteristics over time.
- To analyze trends in HF subtypes, comorbidities, and treatments.
- To provide population-level insights from the Vision C+ electronic medical record.
Main Methods:
- Retrospective cross-sectional analysis of adult patients in Quebec outpatient HF clinics (1998-2021).
- Utilized the Vision C+ electronic medical record for baseline data at inscription.
- Compared patient data across two periods: 1998-2009 and 2010-2021.
Main Results:
- Analyzed data from 63,755 patients (median age 77, 65% male).
- HF with preserved ejection fraction increased (31% vs 26%) in the later period.
- New York Heart Association class III-IV and ischemic etiology decreased in the later period.
Conclusions:
- The Vision C+ dataset provides the first comprehensive description of outpatient HF populations.
- Later periods show increased HF with preserved ejection fraction, high multimorbidity, and reduced ischemic disease.
- These findings highlight evolving HF patient profiles in specialized clinics.
Background:
Heart failure (HF) affects over 750,000 Canadians and remains a major cause of hospitalization. Although specialized HF clinics deliver structured multidisciplinary care, population-level data describing patients followed in these settings are limited. Vision C+, established in 1998, provides a comprehensive dataset to evaluate changes in HF characteristics across Quebec.
Methods:
We conducted a retrospective cross-sectional analysis of adults followed in Quebec outpatient HF clinics between 1998 and 2021 using the Vision C+ electronic medical record. Baseline data at inscription were analyzed and compared across periods (1998-2009 and 2010-2021). Analyses were descriptive and were based on available data without imputation.
Results:
Data of 63,755 patients were analyzed (1998-2009: 14,908; 2010-2021: 48,847), with a median age of 77 years (quartile 1-quartile 3: 67-85), and 65% were male. HF with reduced ejection fraction (left ventricular ejection fraction ≤ 40%) remained predominant (70%), while HF with preserved ejection fraction (left ventricular ejection fraction > 40%) was higher in 2010-2021 (31% vs 26%). New York Heart Association functional class III-IV was higher in 1998-2009 (58% vs 39%), as was ischemic etiology (84% vs 56%). Comorbidities were highly prevalent overall, with small between-period differences observed (all P < 0.001). Cardiac resynchronization therapy with defibrillator use was higher in 2010-2021, whereas coronary revascularization was higher in 1998-2009.
Conclusions:
This first comprehensive description of the Vision C+ dataset shows outpatient HF populations with higher proportions of HF with preserved ejection fraction, substantial multimorbidity, and lower ischemic disease in the later period.
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