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[Surgical treatment of meningococcal infection in children]

L I Budkevich1,2, G V Mirzoyan2, V V Soshkina2

  • 1Veltishchev Research Clinical Institute of Pediatrics and Pediatric Surgery, Moscow, Russia.

Khirurgiia
|August 19, 2026
PubMed

Insights

Generalized meningococcal infection in children is severe and life-threatening. This study details its pathogenesis, diagnosis, intensive care, and surgical treatments, including amputation, for better outcomes.

Area of Science:

  • Pediatric combustiology
  • Infectious diseases
  • Critical care medicine

Background:

  • Generalized meningococcal infection presents severe clinical courses in children.
  • High risks include disabling complications, life-threatening conditions, and mortality.
  • Understanding pathogenesis is crucial for effective management.

Purpose of the Study:

  • To describe the pathogenesis of generalized meningococcal infection in pediatric patients.
  • To highlight challenges in diagnosing and managing septic shock.
  • To outline surgical restoration methods and amputation guidelines.

Main Methods:

  • Review of pathogenesis mechanisms.
  • Analysis of clinical case examples focusing on diagnosis and intensive care.
  • Substantiation of surgical techniques for tissue restoration.
  • Definition of indications and timing for amputation.

Main Results:

  • Late diagnosis and intensive care issues in septic shock were observed.
  • Surgical restoration methods for skin and tissue damage were substantiated.
  • Clear indications and timing for amputation were defined for severe cases.

Conclusions:

  • Effective management requires timely diagnosis and appropriate intensive care.
  • Surgical interventions, including amputation, are vital for managing severe sequelae.
  • Adherence to defined guidelines can improve patient outcomes in pediatric meningococcal disease.

Keywords:
amputationchildrengraftinghydrosurgical treatment of woundsmeningococcal infectionsplit-thickness grafttangential excisionwounds

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