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Published on: July 1, 2020

Trichosporon fungemia in critically ill patients: A case series

S Kataria1, S Pradhan, E Rajni

  • 1Department of Microbiology, Mahatma Gandhi University of Medical Science and Technology, Jaipur, Rajasthan, India.

Journal of Postgraduate Medicine
|August 19, 2026
PubMed

Insights

Trichosporon fungemia, a serious fungal infection, poses diagnostic challenges and high mortality in critically ill patients. Early recognition and antifungal treatment are crucial for improving outcomes in these vulnerable individuals.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Trichosporon species are opportunistic pathogens causing diverse infections, from superficial to life-threatening disseminated disease.
  • Diagnosing Trichosporon infections is difficult due to rarity, misidentification as Candida, and antifungal resistance, delaying treatment.
  • Critically ill patients are particularly vulnerable to severe Trichosporon infections.

Purpose of the Study:

  • To report a case series of Trichosporon fungemia in critically ill patients.
  • To highlight the varied clinical presentations and outcomes of Trichosporon fungemia.
  • To emphasize the need for improved diagnosis and management strategies.

Main Methods:

  • Retrospective case series analysis.
  • Review of clinical data for six critically ill patients with blood culture-confirmed Trichosporon fungemia.
  • Analysis of comorbidities, clinical presentations, and treatment outcomes.

Main Results:

  • Six critically ill patients presented with Trichosporon fungemia.
  • Common comorbidities included diabetes, hypertension, sepsis, and indwelling device complications.
  • The overall mortality rate was high at 66.7% (4/6 cases).

Conclusions:

  • Trichosporon fungemia is associated with significant morbidity and mortality in critically ill patients.
  • Prompt diagnosis, appropriate antifungal therapy, and strict infection control are essential.
  • Further research is needed to improve diagnostic accuracy and therapeutic options.
Keywords:
Chronic kidney diseasefungemiaimmunocompromised hosttrichosporontrichosporonosis

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