Related Experiment Video
Updated: Aug 21, 2026
Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Polymeric clip versus endoscopic stapler for securing the base of the appendix during laparoscopic appendectomy: An
Ratnakar Namdeo1, Manjunath Maruti Pol, Manav Manohar
1Department of Surgical Disciplines, AIIMS, New Delhi, India.
Introduction:
Laparoscopic appendectomy (LA) is the standard of care for acute appendicitis, but the optimal method for appendiceal stump closure remains debated. Endoscopic staplers (ESs) are widely used but expensive, whereas polymeric clips (PCs) offer a cheaper alternative.
Patients And Methods:
We conducted a single-centre, open-label, exploratory randomised controlled trial (September 2021-August 2023) comparing PC (Group A, n = 30) versus ES (Group B, n = 30) for stump closure during LA. Primary outcomes included safety and cost-effectiveness; secondary outcomes included ease and time of application, operative time, hospital stay and complications. Learning curve analysis was performed for a trained surgical resident.
Results:
Sixty patients (mean age: 30.7 ± 11.6 years) were randomised. Demographics and appendicitis severity were comparable between groups. No stump dehiscence occurred in either group. Operative time was similar (55.1 ± 12.8 vs. 54.5 ± 15.4 min, P = 0.86), although application time was longer with PC (80.1 ± 10.0 vs. 68.3 ± 10.9 s, P < 0.0001). Post-operative complication rates were comparable. Total cost was significantly lower with PC (₹79,815 ± 4,072) versus ES (₹1,19,732 ± 16,061; P < 0.0001). Learning curve analysis showed residents required ~20 cases to achieve operative efficiency.
Conclusions:
PCs are a safe, technically simple and cost-effective alternative to staplers for appendiceal stump closure in LA, with comparable outcomes and a short learning curve. Larger multicentre RCTs are warranted.
