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Substitution-induced allosteric activation of coagulation factor IX as a potential alternative hemophilia A treatment

Viola J F Strijbis1, Ka Lei Cheung1, Dorothea Gobbo1

  • 1Dept. of Internal Medicine, Div. of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.

Thrombosis Research
|August 19, 2026
PubMed

Keywords:
Factor IXFactor VIIIaHemophilia ARecombinant proteinsSerine protease

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