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Updated: Aug 21, 2026

Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition
Published on: January 5, 2024
Radioxenon calibration, quality control, and intercomparison exercises
Troy Robinson1, Mattias Aldener2, Matthew Goodwin3
1INL, United States.
None:
The Idaho National Laboratory (INL, USA), serves as a quality control laboratory for the Comprehensive Test Ban Treaty Organization. Unfortunately, INL lost its primary source of traceable 133Xe materials when the National Institute of Standards and Technology (NIST, USA) stopped producing this standard reference material. To address this gap, INL collaborated with the National Physical Laboratory (NPL, UK) in 2017 and 2018 through interlaboratory comparison experiments to validate INL's133Xe calibration. Following successful completion of these intercomparisons, two additional intercomparisons were performed in 2020 and 2021, incorporating a second radionuclide (131mXe) and three additional CTBTO affiliated analysis laboratories: Pacific Northwest National Laboratory (PNNL, USA), the Atomic Weapons Establishment (AWE, UK), and the Swedish Defense Research Agency (FOI, Sweden). Intercomparison results from all four exercises are presented and discussed.
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