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Follicular Lymphoma Involving the Supraglottic Larynx in a Patient with Recurrent Cutaneous B-cell
Ryohei Asai1, Hiroumi Matsuzaki1, Shimon Otake2
1Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Japan.
Abstract:
We report a rare case of follicular lymphoma involving the supraglottic larynx in an elderly woman with progressive hoarseness and potential airway compromise. Microlaryngoscopic resection was performed before systemic staging. Histopathology showed grade 1-2 follicular lymphoma. Postoperative FDG PET/CT and a bone marrow biopsy revealed no nodal, visceral, or bone marrow involvement at diagnosis. Because the clonal relationship with previous cutaneous B-cell lymphoproliferative lesions could not be assessed, a primary laryngeal origin could not be established. Involved-site radiotherapy was proposed, but declined by the patient. The patient remained free of local recurrence 6 months after surgery.