Related Experiment Video

Updated: Aug 21, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

Systematic profiling reveals broad G protein coupling and context-dependent modulation of cyclic AMP by the orphan

Boris Trapkov1, Hans Bräuner1, Alexander Sebastian Hauser1

  • 1Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

British Journal of Pharmacology
|August 20, 2026
PubMed
Abstract

Keywords:
CNSG protein couplingGPR139arrestincAMPorphan GPCRsignalling biassignalling mechanismssignalling regulation

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