Related Experiment Video

Updated: Aug 21, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

Discovery of VU6052959/BI'7927: A Selective mGlu3 Positive Allosteric Modulator (PAM) from an Orthogonal Benzoxazine

Caleb A Jones1,2, Renn A Duncan1,2, Kristen M Gilliland1,2

  • 1Warren Center for Neuroscience Drug Discovery, Vanderbilt Institute for Therapeutic Advances, Vanderbilt University, Nashville, Tennessee 37232, United States.

ACS Medicinal Chemistry Letters
|August 20, 2026
PubMed

Keywords:
PAMcognitionmGlu3metabolismmetabotropic glutamate receptor subtype 3novel object recognitionpharmacokineticspositive allosteric modulator

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