Related Experiment Videos
Incidence Trends and Disease Burden of Vascular Intestinal Disorders: A Population-Based Study in China and Worldwide
Lanhui Zeng1, Bowen Li1, Junhui Gao1
1Department of Interventional and Vascular Surgery, Affiliated Hospital of Jinggangshan University, Ji'an, Jiangxi, 343009, People's Republic of China.
Purpose:
Vascular intestinal disorders (VID), characterized by inadequate intestinal perfusion, lead to severe complications like tissue ischemia, infarction, and inflammation. This study evaluates global and Chinese VID trends and burden from 1990 to 2021 using Global Burden of Disease (GBD) 2021 data.
Methods:
Age-standardized incidence, prevalence, mortality, and disability-adjusted life years (DALYs) were extracted. Joinpoint regression analyzed temporal trends, computing average annual percentage changes (AAPC) and 95% confidence intervals. Subgroup analyses covered age, sex, and socio-demographic index.
Results:
Globally, the age-standardized incidence rate (ASIR) declined from 18.81 to 15.98 per 100,000 (AAPC: -0.52%); in China, it fell from 5.92 to 5.03 (AAPC: -0.50%). However, China's absolute cases nearly doubled due to demographic shifts. Significant gender and age disparities emerged: younger males showed higher ASIR and ASMR, while women ≥75 years had elevated morbidity and mortality.
Conclusion:
Despite declining age-standardized rates, the absolute VID burden escalates globally and in China. Disparities disproportionately affect elderly women and younger males. Enhanced diagnostics, equitable access, and targeted prevention are urgent. Stakeholders must prioritize integrative VID prevention strategies within non-communicable disease frameworks to mitigate this growing concern.
Related Concept Videos
01:17Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
01:25Inflammatory Bowel Disease III: Crohn's Disease