Amniotic fluid embolism. A report of three cases

Area of Science:

• Obstetrics and Gynecology
• Critical Care Medicine
• Pathology

Background:

• Amniotic fluid embolism (AFE) is a rare but catastrophic obstetric emergency.
• Characterized by sudden cardiopulmonary collapse, coagulopathy, and potential fetal distress.
• Early recognition and management are crucial for maternal survival.

Observation:

• This report details three cases of patients presenting with clinical features consistent with AFE.
• Two patients experienced AFE and survived the acute event.
• The third patient, unfortunately, succumbed to the condition, with diagnosis confirmed by post-mortem lung histology.

Findings:

• Histological examination of lung tissue is definitive for confirming AFE.
• Survival is possible in AFE cases, highlighting the importance of timely intervention.
• The study underscores the varied clinical presentations and outcomes of AFE.

Implications:

• Increased awareness of AFE's typical and atypical presentations is vital for clinicians.
• Post-mortem histological confirmation remains the gold standard for AFE diagnosis.
• Further research into AFE pathophysiology and improved management strategies is warranted.