Disorders of Water and Tissue Perfusion (Diabetes Insipidus, Renin-Angiotensin-Aldosterone Axis, and Anhidrosis)
1Department of Large Animal Medicine, University of Georgia College of Veterinay Medicine, 2200 College Station Road, Athens, GA 30605, USA.
Abstract:
This review highlights disorders of water and tissue perfusion in equids, specifically diabetes insipidus, the renin-angiotensin-aldosterone axis, and anhidrosis. The differences in renal versus central diabetes insipidus is discussed, as well as diagnosis and treatment of diabetes insipidus in equids. The physiology of the renin-angiotensin-aldosterone axis is reviewed, and recent research in the role of the renin-angiotensin-aldosterone axis in equids in certain states is emphasized. The proposed pathophysiology of anhidrosis in horses is discussed, as well as potential therapies.
Related Concept Videos
Diabetes Insipidus I: Introduction
Diabetes Insipidus II: Pathophysiology
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Heart Failure Drugs: Diuretics

