Jejunal diverticulitis with misleading biochemical improvement: a diagnostic challenge

Jejunal diverticulitis is a rare and often under-recognized cause of acute abdominal pain, frequently presenting with non-specific clinical, biochemical, and radiological findings. A 52-year-old female presented with acute abdominal pain and elevated inflammatory markers, but non-diagnostic imaging. Despite biochemical improvement with conservative management, her symptoms persisted. Diagnostic laparoscopy revealed jejunal diverticulitis with an incidental Meckel's diverticulum requiring dual segmental small bowel resection. The postoperative course was uneventful. This case highlights the limitations of relying on biochemical and radiological findings in isolation. Persistent symptoms despite reassuring investigations should prompt consideration of operative exploration.