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Published on: August 10, 2018
[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in
Wei Kang1, Joanna H M Tong1, Anthony W H Chan1
1Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, P.R. China.
Abstract:
Subsequently to the publication of the above article, an interested reader drew to the Editor's attention that apparently the same set of GADPH data panels had been featured in a number of research articles by this group, even though it appeared as if these were intended to have shown the same experimental conditions in most cases. The authors have realized that the GAPDH loading control panel in question, shown in Fig. 1C on p. 2581, had been inappropriately used to represent the same batch of tissue samples in several articles. Although the tissue samples were from the same batch, the authors recognize that using the same GAPDH panel as the loading control across a number of different publications was inappropriate. To address this issue, the authors have replaced both the RRM2 and the GAPDH data in Fig. 1C of the above paper, and the revised version of Fig. 1 is shown on the next page. In addition, upon re‑examining their original data, the authors also realized that certain images captured for the invasion assay in Fig. 3C on p. 2584 contained overlapping sections (for example, the 'Scramble siRNA' and 'RPM2 siRNA' data panels for the AGS cell line). Therefore, the invasion assay experiments were also repeated, and the corresponding panels in Fig. 3C have been replaced. The revised version of Fig. 3 is shown on the second subsequent page. The authors wish to emphasize that the errors made in assembling the data in these figures did not affect the overall conclusions reported in the paper. The authors are grateful to the Editor of Oncology Reports for granting them this opportunity to publish a Corrigendum, and apologize to both the Editor and the readership for any inconvenience caused. [Oncology Reports 31: 2579‑2586, 2014; DOI: 10.3892/or.2014.3148].
Insights
This corrigendum addresses the inappropriate reuse of GAPDH loading control data and overlapping images in invasion assays. The authors have reissued corrected figures, emphasizing that core conclusions remain unaffected.
Area of Science:
- Oncology
- Molecular Biology
- Scientific Publishing Ethics
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