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Can Artificial Intelligence Match Human Expertise in Long-Term Periodontal Prognosis? A Comparative Accuracy Study
Pablo Antonio López-Galindo1, Giuseppe Troiano2, Matteo Serroni1,3
1Department of Periodontics and Preventive Dentistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Aim:
To compare the prognostic performance of an artificial intelligence (AI) model with that of experienced clinicians in predicting tooth loss over a 10-year period.
Materials And Methods:
An AI model trained on structured clinical and radiographic data was compared with 12 periodontists and 11 general dentists (GDs), who independently assigned prognostic scores (0-10 scale) to 300 teeth with known 10-year outcomes. AI and clinician performance were evaluated under a fixed threshold and group-specific optimal thresholds. Accuracy, sensitivity, specificity, predictive values, area under the receiver operating characteristic curve and calibration were used for comparison.
Results:
Using the fixed threshold (score > 5 = survival), clinicians achieved higher overall accuracy than AI (75.6% periodontists, 74.9% GDs, 69.2% AI; p < 0.05), with sensitivity low and comparable across groups (14.7%-22.7%). Using group-specific optimal thresholds, AI achieved the highest accuracy for all-cause tooth loss (67.5%) and performed comparably to GDs for periodontitis-related tooth loss (76.2% vs. 76.3%). Calibration was substantially worse for AI (Brier score 0.247) than for periodontists and GDs (0.171, 0.170). Individually, AI performance overlapped with that of several clinicians.
Conclusion:
Clinicians outperformed AI under a fixed threshold, but AI performance was comparable to clinicians using optimal thresholds, situating AI within the range of experienced clinicians despite modest overall predictive ability.