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Recurrent and Progressive CAVB After Alcohol Septal Ablation for HOCM: Bridging Therapy With a Semi-Permanent

Enyuan Zhang1,2, Le He2, Henan Zhang2

  • 1Tianjin Medical University Tianjin China.

Clinical Case Reports
|August 22, 2026
PubMed

Insights

Alcohol septal ablation for hypertrophic obstructive cardiomyopathy can cause delayed atrioventricular block. Semi-permanent pacemakers offer effective bridging therapy, monitoring conduction recovery and potentially avoiding permanent device implantation.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Alcohol septal ablation is a treatment for hypertrophic obstructive cardiomyopathy.
  • Complete atrioventricular block is a potential complication following this procedure.
  • This block can manifest late and recur, posing management challenges.

Purpose of the Study:

  • To evaluate the role of semi-permanent pacemakers in managing delayed and recurrent atrioventricular block after alcohol septal ablation.
  • To assess the efficacy of pacemakers as a bridging therapy in this patient population.

Main Methods:

  • Retrospective analysis of patients who underwent alcohol septal ablation.
  • Inclusion of patients who developed delayed or recurrent complete atrioventricular block.
  • Utilization of semi-permanent pacemakers for temporary pacing and monitoring.

Main Results:

  • Semi-permanent pacemakers provided effective bridging therapy for delayed atrioventricular block.
  • Pacemaker use allowed for extended monitoring of cardiac conduction recovery.
  • Selected patients were potentially spared from permanent pacemaker implantation.

Conclusions:

  • Semi-permanent pacemakers are a valuable tool in managing delayed and recurrent atrioventricular block post-alcohol septal ablation.
  • This approach facilitates monitoring and may reduce the need for permanent device implantation in select cases.
  • Consideration of semi-permanent pacing is warranted for patients experiencing conduction disturbances after septal ablation.

Keywords:
alcohol septal ablationcomplete atrioventricular blockhypertrophic obstructive cardiomyopathysemi‐permanent pacemaker

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