Skin response to histamine in systemic lupus erythematosus

A comparative study of skin responses to histamine in systemic lupus erythematosus (SLE) patients and in a control group suggests that although there are individual differences in response, the SLE patients responded sooner to 1:100 dilution. Since the test did not result in any ill effect it is concluded that existing clinical methods of testing and treatment of SLE patients having allergies are safe from the viewpoint of the histamine effect.