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Published on: May 4, 2020
A Case of Asymptomatic Lead Poisoning in a Two-Year-Old With a Background of Pica and Iron Deficiency Anaemia
Rafia Ayub1, Inayat K Hafiz2, Ahsan Ul-Haq2
1Internal Medicine, Manchester University NHS Foundation Trust, Manchester, GBR.
Insights
Asymptomatic lead poisoning in children can be detected through screening, especially in those with risk factors like pica. Early identification and chelation therapy are crucial for preventing long-term complications.
Area of Science:
- Pediatrics
- Toxicology
- Environmental Health
Background:
- Lead poisoning is a significant, often overlooked, pediatric health issue.
- Children with pica and iron deficiency anemia are at increased risk.
- Asymptomatic cases pose diagnostic challenges.
Abstract:
Lead poisoning remains an important yet under-recognised cause of morbidity in children. We report the case of a two-year-old child presenting with asymptomatic lead poisoning identified following investigation of pica, including ingestion of wall paint. This was with concomitant iron deficiency anaemia secondary to excessive cow's milk intake. Given these significant risk factors, blood lead level screening was done despite her asymptomatic presentation, revealing a markedly elevated lead level of 3.34 µmol/L (reference range ≤ 0.10 µmol/L). Following these results, she was admitted for treatment with chelation therapy under the guidance of the National Poisons Information Service (NPIS), with ongoing surveillance in clinic to monitor treatment response and ensure a decline in blood lead levels. This case highlights the diagnostic challenges of asymptomatic lead poisoning and emphasises the importance of having a low threshold for screening in children with risk factors, including pica, nutritional deficiencies, and potential environmental lead exposure. Early recognition can facilitate timely treatment, reducing the risk of long-term complications.
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