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When Hemiplegic Migraine Defies Expectations: Diagnostic Complexity in a Rare Genetic Disorder

Amandine Goossens1, Ann-Laurence Delabie1, Tanguy Demaret2

  • 1Department of Neurology, Centre Hospitalier Universitaire Tivoli, Université libre de Bruxelles (ULB), La Louvière, Belgium.

Case Reports in Neurology
|August 23, 2026
PubMed
Abstract

Insights

Familial hemiplegic migraine (FHM) can present with diverse neurological symptoms, mimicking other serious conditions. Accurate diagnosis relies on detailed clinical history and genetic testing to ensure proper management.

Area of Science:

  • Neurology
  • Genetics

Background:

  • Familial hemiplegic migraine (FHM) is a rare inherited migraine subtype with aura.
  • FHM is characterized by reversible motor aura and a broad range of neurological symptoms, complicating diagnosis.
Keywords:
Case reportHemiplegiaMigraineSomnolenceVasospasm

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