Related Experiment Video
Updated: Aug 26, 2026

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
Published on: June 17, 2022
Co-design of the Implementation Toolkit for Small and Sick Newborn Care: a global open-access knowledge management
Lauren E Allison1, Mbozu Sipalo2, Tobias Whatley2
1Department of Infectious Disease Epidemiology and International Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. lauren.allison@lshtm.ac.uk.
Background:
Most births worldwide (> 80%) occur in health care facilities, yet 2.3 million newborns die annually. If the know-do gap between evidence and implementation was closed, an estimated 752,000 newborn deaths could be prevented per year. We describe the co-design of the Implementation Toolkit (Newborn Toolkit) for Small and Sick Newborn Care (SSNC), a web platform and linked community of global implementers, facilitated by NEST360 and UNICEF to enable access to curated resources, including guidelines, practical tools and peer learning for contextual adaptation.
Methods:
A systematic three step co-design process was followed. Step 1) Structure: We used an organising framework of WHO and UNICEF ten core components for systems strengthening for SSNC. We then reviewed relevant knowledge management platforms to identify elements facilitating user engagement. Step 2) Content: > 300 implementers collated publications and tools according to the ten core components. Step 3) Refining and building community: User data analytics plus direct feedback from the global communities of practice provided data to improve website content and community uptake, notably regular webinars.
Results:
Step 1) Structure: In 2020, the Newborn Toolkit website structure was co-designed based on the ten core components. Step 2) Content: Working groups, organised by core components, collated over 1,100 resources in 15 languages. Step 3) Refining and building community: Cross-country learning was facilitated through 45 webinars with multi-disciplinary speakers from all continents including caregivers, clinicians, non-governmental organisation representatives, engineers, and data scientists. French language translation and engagement was added between 2023-2025. Unique user counts increased with 28,146 in 2023 to 62,561 in 2025 from 198 countries and territories. The most viewed content includes WHO guidelines, neonatal floor plans, the ABC device costing tool, and data tools.
Conclusions:
Given the urgency for accelerated progress for newborn survival by 2030, faster implementation of proven solutions is needed. It is crucial that implementers can access evidence and tools to adapt for their specific context, rather than "reinventing the wheel". Systems change is complex, requiring novel approaches to make it doable, such as standard, simplified action pathways available on the Newborn Toolkit. Gaps to address include evidence availability in multiple languages.
Related Concept Videos
Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Nursing Implementation
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution itself.
International Nursing Organizations II
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...
International Nursing Organizations I
ICN member organizations work to advance the field of nursing and healthcare via policies, partnerships, lobbying, professional...
