Related Experiment Video
Updated: Aug 26, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Risk factors associated with multidrug-resistant pulmonary tuberculosis in patients over 15 years old: a
Odete Bambi Receado1, Paulo Ney Solary2, Emanuel Catumbela3
1Department of Public Health, Faculty of Medicine, Agostinho Neto University, Luanda, Angola.
Introduction:
Multidrug-Resistant Pulmonary Tuberculosis (MDR-TB) represents a serious public health problem, hindering disease control and increasing morbidity and mortality. This study aimed to identify risk factors associated with MDR-TB in patients over 15 years old at the Sanatorium Hospital of Luanda during the period 2015-2016.
Methods:
A retrospective case-control study (1:1) was conducted with 500 participants, including 250 cases (MDR-TB) and 250 controls (drug-sensitive TB). Data were obtained from clinical records and analyzed using logistic regression in Epi-Info 7.2.1.0 software, considering a significance level of p < 0.05.
Results:
MDR-TB was more prevalent in men (61.6%), in the age group 20-29 years (36.8%), and among employed individuals (73.2%). The associated risk factors were irregular medication adherence [odds ratio (OR) = 12.3; p < 0.001], previous TB treatment (OR = 9.0; p < 0.001), contact with an MDR-TB patient (OR = 4.1; p < 0.001), and lower educational level (OR = 2.1; p = 0.03).
Conclusion:
Irregular adherence to treatment and a history of previous TB were the main factors associated with MDR-TB, reinforcing the need for effective strategies to ensure treatment follow-up.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Tuberculosis
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
