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Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor
09:33

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

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Community-driven updates for comprehensive long-read metagenomics and enhanced binning in nf-core/mag v5

Diego Alvarez Saravia1,2, Adam Rosenbaum3, Daniel Straub4,5

  • 1Department of Computer Engineering, Universidad de Magallanes, Av. Bulnes 01855, Punta Arenas, 6200000, Magallanes, Chile.

Bioinformatics (Oxford, England)
|August 25, 2026
PubMed
Abstract

Keywords:
Nextflowde novo assemblymetagenome assembly genomesmetagenomic assemblynf-corpipeline

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.