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Updated: Aug 27, 2026

Murine Kidney Transplant Technique
Published on: October 20, 2015
Infected wound in a lower extremity hematoma in a patient with thrombocytopenia after renal transplantation
Hongyu Wang1, Lin Chen2, Qian Gao1
1Wound Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background:
Renal transplantation is a highly effective treatment for end-stage renal failure. However, prolonged administration of immunosuppressive agents is necessary, which may elevate the risk of infection, particularly in cases associated with injury. These medications have the potential to induce thrombocytopenia, which can complicate wound management, because mechanical debridement is contraindicated in such cases. The paucity of literature on infected hematoma following renal transplantation is striking.
Case Report:
The case reported herein is that of a hematoma wound infection located on the skin of the lower extremity, which occurred as a result of a car accident that took place 20 years after renal transplantation. The patient had been experiencing thrombocytopenia due to prolonged immunosuppressant therapy for 2 months prior to this incident. A combination of ultrasonic debridement and moist wound dressings was used for effective management of the infected wound.
Conclusion:
The successful use of ultrasonic debridement in conjunction with autolytic debridement can not only prevent bleeding during debridement but also effectively remove necrotic tissue, thereby promoting favorable wound healing and enabling patients to resume normal daily life.
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