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Editors Highlights-October 2026
1Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary.
Abstract:
The treatment of inflammatory skin diseases has moved from broad immunosuppression toward mechanism-based therapy with targeted biologics and small molecules. Psoriasis exemplifies this shift: interleukin-23 (IL-23)/T helper 17 (Th17) blockade can achieve near-complete clearance, yet persistent tissue-resident memory T cells may sustain disease memory and drive relapse after treatment withdrawal. The papers highlighted in this issue link tissue memory, genotype, treatment durability, and pathway-directed therapy across different skin diseases. Together, they emphasize that precision dermatology must look beyond visible clearance toward biological remission and durable disease control.
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