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Updated: Aug 28, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
Esophageal cancer-associated thoracic central venous obstruction type 2 which occurred during chemoradiotherapy
Yoshiki Tokunaga1, Kohei Hayashi1, Rie Uehara1
1Department of Gastroenterology and Hepatology, Graduate School of Biomedical Sciences, Nagasaki University, Japan.
Abstract:
Thoracic central venous obstruction (TCVO) can cause facial and upper extremity edema and it is often associated with malignancies. We herein report a rare case of cervical esophageal squamous cell carcinoma complicated by TCVO type 2 during chemoradiotherapy. Approximately 1 week after starting 5-fluorouracil plus cisplatin with radiotherapy, the patient developed acute painful swelling of the left arm. Contrast-enhanced computed tomography revealed thrombosis of the left internal jugular vein with extrinsic compression of the ipsilateral subclavian vein by a cervical tumor. Symptoms improved after anticoagulation therapy while chemoradiotherapy was continued, although the improvement was likely multifactorial.
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