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Structural Modification of Sesquiterpene Lactones via Michael Addition: Improved Bioactivity and Pharmacokinetics

Min Woo Ha1,2, Jayun Kang1,2, Sumi Lee3

  • 1Jeju Research Institute of Pharmaceutical Sciences, College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea.

International Journal of Molecular Sciences
|August 27, 2026
PubMed

Keywords:
Michael additiondrug-target interactionspharmacokineticssesquiterpene lactonesstructural optimizationα-methylene-γ-lactone

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