Perceived Stress and Domain-Specific Physical Activity in Relation to Anxiety and Somatic Symptom Burden Among...

Background and Objectives: Physical activity may relate to mental health differently depending on whether it is performed at work, for transport, or during leisure. Evidence regarding this distinction in Romanian community samples remains limited, and it is unclear whether these associations persist after accounting for perceived stress. We examined domain-specific physical activity, sedentary time and perceived stress in relation to anxiety and somatic symptom burden. Materials and Methods: This cross-sectional online survey included 307 Romanian adults aged 18-65 years. Physical activity was measured with the Global Physical Activity Questionnaire, perceived stress with the 14-item Perceived Stress Scale, anxiety with the Beck Anxiety Inventory, and somatic symptoms with the Patient Health Questionnaire-15. Spearman correlations were adjusted for multiple testing with the Benjamini-Hochberg false-discovery-rate procedure. Multivariable linear models used HC3 robust standard errors and included sex, age group, education, body mass index and religious affiliation as covariates. Scores for each physical activity domain were log(1 + x)-transformed and standardized. Sensitivity analyses considered participation versus non-participation, symptom severity categories, total activity and exclusion of an extreme activity value. Results: Median scores were 24 for perceived stress, 10 for anxiety and 7 for somatic symptoms. Perceived stress correlated with both anxiety (rho = 0.486) and somatic symptoms (rho = 0.428; both false-discovery-rate-adjusted p < 0.001). Vigorous leisure-time activity was inversely correlated with somatic symptoms (rho = -0.205; adjusted p = 0.002), whereas total physical activity was not associated with either outcome. In the fully adjusted models, a one-standard-deviation-higher PSS-14 score was associated with 5.57 more BAI points (95% CI 4.50-6.63) and 2.12 more PHQ-15 points (95% CI 1.62-2.63). Vigorous leisure-time activity remained associated with a lower PHQ-15 score (-0.84 points per standard deviation; 95% CI -1.35 to -0.32), but its association with BAI was no longer statistically significant after adjustment for perceived stress. Conclusions: Perceived stress showed the strongest association with both anxiety and somatic symptom burden. The use of a single total activity score concealed a more specific inverse association between vigorous leisure-time activity and somatic symptoms. Longitudinal studies using more representative sampling, objective measures of activity and broader confounder assessment are needed to clarify directionality and determine the potential relevance of vigorous leisure-time activity to somatic symptom burden.