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Absence of Mycoplasma genitalium Strains Simultaneously Harboring Wild-Type gyrA, parC, and 23S rRNA Genes in Japan:
Ayane Nishino1, Natsumi Haba1, Seiya Sawada1
1Cancer Genomic Testing and Treatment Center, Central Japan International Medical Center, Minokamo, Gifu, Japan.
Abstract:
Using next-generation sequencing, we analyzed fluoroquinolone and macrolide resistance-associated mutations of the gyrA, parC, and 23S rRNA genes in Mycoplasma genitalium and detected mutations in 22.3% (37/166), 92.5% (161/174), and 96.0% (169/176), respectively, in Japan. No strains harboring 3 wild-type genes were identified, indicating widespread dissemination of antimicrobial resistance.
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