Regional Stabilization Before Transfer in Moderate Traumatic Brain Injury: Comparable Outcomes Within a Rural...

BackgroundThe Brain Trauma Foundation's guidelines specifically highlight the need to determine optimal triage destination for moderate traumatic brain injury (modTBI) patients, particularly in rural settings where Level I trauma centers may be geographically distant.MethodsRetrospective cohort analysis utilizing sequential adult patients (≥18 years) with modTBI, defined by a field Glasgow Coma Scale (GCS) score of 9-13, admitted to two Level-1 trauma centers (2017-2024). Patients were divided into two groups based on initial triage: initial assessment at regional centers with subsequent transfer (n = 60) vs direct admission to Level I trauma centers (n = 148). Outcomes included hospital discharge disposition, hospital interventions, complications, and functional outcomes as measured by the Glasgow Outcome Scale-Extended (GOSE) at six months. Statistical analysis involved chi-square and Mann-Whitney U tests, with sensitivity analyses to address missing six-month follow-up data.ResultsBaseline injury severity and imaging findings were comparable between groups. The Transfer group had fewer surgical interventions (26.7% vs 52.7%, P < .002). There were no significant differences in hospital mortality (21.7% vs 14.2%, P = 0.27), home discharge (28.3% vs 34.5%, P = 0.49), or hospital complications (23.3% vs 29.7%, P = 0.40). At six months, Favorable outcomes (GOSE 5-8) were comparable between groups (65.9% vs 74.8%, P = 0.38), as were six-month mortality rates (16.7.% vs 8.8%, P = 0.16). Sensitivity analyses remained robust under most missing data assumptions.DiscussionInitial triage location did not significantly affect discharge disposition, complication rates, or six-month functional outcomes in modTBI patients. Hub-and-spoke triage appears safe for hemodynamically stable modTBI in rural trauma systems with established transfer networks.