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Study Protocol for Assessment of the Feasibility of an Intraoperative Localization Technique Using Augmented Reality
Alexia Giro1,2,3, Judith Passildas1,2,3, Emilie Thivat1,2,3
1Division de Recherche Clinique, Délégation Recherche Clinique & Innovation, Centre Jean Perrin Centre de Lutte contre le Cancer Clermont-Ferrand France.
Background And Aims:
Localizing non-palpable cancerous lesions of breast-conserving surgery is a major challenge. Augmented reality (AR) and 3D imaging are emerging tools for surgical guidance. This study evaluates the feasibility of a noninvasive intraoperative localization technique using AR.
Methods:
This prospective, interventional, single-center proof-of-concept study investigates AR-assisted localization of non-palpable breast lesions. Secondary objectives include surgical time assessment, breast phantom development, and fusion feasibility between supine 3D breast MRI images and post-MRI ultrasound with target lesion detection. The study includes an additional MRI in supine position and intraoperative 3D images of the patient's chest captured with a 3D camera. A 3D reconstruction of the patient's chest and lesions will be performed from the MRI images, called the preoperative 3D model. A total of five patients eligible for assessment are expected.
Conclusion:
The challenge of this study is the development of a noninvasive intraoperative localization technique using AR from preoperative images in breast-conserving surgery. If this study is successful, a randomized trial will be designed to compare the accuracy of the intraoperative localization technique using AR with that of the gold standard intraoperative breast ultrasound.
